Psilocybin may curb opioid use disorder
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Researchers claim that psychedelics can help people with opioid use disorder. The usage of traditional psychedelics may reduce the risk of developing opioid use disorder.
Researchers analyzed data from The National Survey on Drug Use and Health from 2015 to 2019 to determine the association between the two factors in the study titled “Associations between classic psychedelics and opioid use disorder in a nationally-representative U.S. adult sample.” People facing homelessness, currently incarcerated residents, and military members on active duty are excluded from the annual study, which looks into the use of substances and associated health outcomes.
Peyote, psilocybin, LSD, and mescaline were the four most commonly used psychedelics in NSDUH logs. Besides demographic factors like race/ethnicity, gender, marital status, self-reported involvement in risky behavior, educational attainment, annual household income, and lifetime use of other substances like sedatives, marijuana, ecstasy, cocaine, and other substances were also taken into consideration by the researchers.
An opioid use disorder diagnosis in the past year, or if a person had been dependent on heroin or prescription painkillers, was the most important dependent variable.
The researchers discovered that psilocybin, sometimes known as magic mushrooms, was the only classic psychedelic that appeared to lessen a person’s risk of OUD at the end of the study. Other population-based research of a similar sort, such as the link between cocaine use disorder and class psychedelics, psilocybin and severe depressive episodes, and psilocybin and criminal arrests in U.S. adults, have shown comparable results.
Opioid use disorder
Opioid abuse is a public health epidemic, with nearly 70,000 deaths in 2017, a 292 percent increase since 2001. Opioids like fentanyl, heroin, and prescription opioid compounds are responsible for around 70% of overdose deaths in the United States. Buprenorphine and methadone are two therapies for OUD, however, they both carry the risk of substituting one addiction for another.
The researchers point out that the study only looks at one aspect of the issue, and that some elements need to be examined further. For one thing, “psychedelic usage” was judged solely on the basis of lifetime use rather than frequency or recency. The obvious result that magic mushrooms can reduce the danger of substance dependence for a long time suggests it can be used in future studies on other therapies.
For the treatment and prevention of opioid use disorder, classic psychedelics may have a role. The findings in the report, these findings provide credence to its application as an addiction treatment.
Future clinical trials will be needed to see if this link is causal, as well as to figure out which mediators may be involved. To determine if psilocybin and OUD are linked, researchers should conduct long-term investigations. Psilocybin and OUD are linked, and these investigations can help establish that link, as well as increase the chance of ethical and safe clinical trials evaluating this compound’s therapeutic potential. This study contributes to the growing body of knowledge on the risk factors for opioid use disorder and how they can be mitigated.